When Joker's pet hyenas, Lex Luthor's pet iguana, and the Penguin's hench-birds try to enact their evil plans, Krypto will team up with his best buddies to save the day. With the help of Ace the Bat-Hound, Streaky the Super-Cat, Comet the Super-Horse, Beppo the Super-Monkey, and even Superman himself, Krypto will discover the power of friendship and teamwork.